"If we want to image something like how a tumor is growing or shrinking, we have a hard time seeing anything significant because the background ultrasound signals from flowing blood drowns everything out," said Junjie Yao, assistant professor of biomedical engineering at Duke. This creates an ultrasonic wave that provides information about the structure and composition of the targeted tissues and cells that can be translated into high-resolution images.īut while the ultrasound component of photoacoustic imaging allows engineers to peer deeper into tissue than traditional imaging, it also introduces a problem: background noise. The imaging process sends a burst of laser light deep into tissue, causing cells to heat up and expand instantaneously. The research appeared May 19 in the journal Nature Communications.Īs its name suggests, photoacoustic imaging (PA) uses both light and sound to capture detailed images of cells, organs and other tissues throughout the body. The approach will help researchers isolate and remove sources of strong background noise in biomedical images, giving them unprecedented access to observe, influence and image biological processes with a swiftly developing imaging technique called photoacoustic imaging.
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